Assoc Prof Andrew Lonie
Head
Life Sciences Computation Centre
Victorian Life Sciences Computation Initiative

Boardroom
Level 2, Alan Gilbert Building
161 Barry Street (Cnr. Grattan and Barry Streets)
Carlton South VIC 3053
AUSTRALIA

Abstract

In 2011 you can sequence a human genome for less than $10,000 in about a week. The world capacity for sequencing is now over 100,000 genomes per year and continues to grow exponentially, driven primarily by rapid advances in massively parallel sequencing technologies. This capacity is catalysing a fundamental transformation of many biological and medical sciences into data-driven sciences. I will attempt to provide an overview of 'next-generation genomics', using case studies from projects we are working on at the Life Sciences Computation Centre. In particular I will look at research approaches enabled by high throughput genomics including genome-wide variant discovery, fusion gene identification, expression profiling and metagenomics, and examine some of the realities of the bioinformatics behind these approaches. I'll also look at some of the large genomic initiatives like dbSBP and 1000Genomes and discuss how they assist in interpretation of the masses of data generated by sequencing a human genome.

There will be a light lunch beforehand in the Boardroom, Level 2, Alan Gilbert Building at 12:30 pm. PLEASE RSVP by Thursday 11 August if you would like to attend the lunch to This e-mail address is being protected from spambots. You need JavaScript enabled to view it